Reginald Q. Knight, MD

Director

Bassett Center for Spine Care
Cooperstown, NY USA
 

Dr. Reginald Knight is a Fellowship trained Board Certified Orthopedic Surgeon. Dr. Knight completed his Doctorate of Medicine at SUNY, NY and then completed a general surgery internship and orthopedic surgical residency at the New York Medical College. Dr. Knight completed his Fellowship in spinal surgery at the University of Rochester School of Medicine at Strong Memorial Hospital in Rochester, NY.

Today, Dr. Knight is Director of the Bassett Healthcare Center for Spine Care.  His practice treats a broad spectrum of spinal disorders. 

Dr. Knight is recognized as a leading researcher in the spine field and has published extensively in the peer-reviewed spine literature.  He regularly teaches at medical conferences worldwide.

Financial Disclosure: 

Research or institutional support has been received from Benvenue; Miscellaneous non-income support (eg, equipment or services), commercially-derived honoraria, or other non-research related funding (eg, paid travel) has been received from: Medtronic, Stryker; Royalties have been received from: Stryker; Consultant or employee: Medtronic, Stryker

Publications 

Peer-reviewed Publications:

  1. A Better Ankle Support. Knight RQ, Roberge D. Emergency Medicine, 16:6, March 1984.
  2. Intraoperative Somatosensory Evoked Potentials: The Rochester Experience. Knight, Chan, Smith, Devanny, and Jackman, Published in the Proceedings from the 3rd International Symposium October 1986.
  3. Incomplete Spinal Cord Injury Syndromes Status Post Aortic Arch Repair. Knight, RQ., and Devanny, JR. Spine Volume 12, Number 6, 1987.
  4. Oxalosis and Accelerated Degenerative Spinal Stenosis: A Case Report. Knight, Taddonio, Smith, Weseley, and Pecker, Orthopaedics, Vol. 11, Number 6, pp. 955-958, June, 1988.
  5. Modified Microdiscectomy: Indications, Technique and Pitfalls. Knight, RQ. Accepted for Publication in Surgical Rounds for Orthopaedics.
  6. Long-Term Follow Up of Posterior Cervical Spine Fusion in Rheumatoid Arthritis. Knight, Cohen, Chan, Transactions of the Association for Academic Minority Physicians, Volume III, Fall/Winter 1989.
  7. Magnetic Resonance Imaging Versus Discography. Knight, RQ, Pain Management Update March/April 1990, pg. 73-75.
  8. Idiopathic Scoliosis with Unusual Stress Fracture of Pedicle Within Solid Fusion: A Case Report. Knight, Chan, Spine, Volume 17:7, 849-851, 1992.
  9. Neurofibromatosis: Progressive Kyphosis of the Cervical Spine with Anterior Cord Syndrome. A Case Report and Literature Review. Knight, Hieb, Journal of Spinal Disorders, Volume 5:4, 1992.
  10. Far Lateral Disc Herniation. Knight, Virginia Mason Clinic Bulletin, Fall 1992, Vol. 46: 66-68.
  11. Influence of Pedicle Fixation on Post-Operative Pain. Knight, Chan, Devanny, DiMaio, Journal of Spinal Disorders, Volume 6:2, 141-145, 1993.
  12. Lumbar Spine Fusion. Knight, Virginia Mason Clinic Bulletin, Vol. 47: 1-12, Spring 1993.
  13. Neurologic Sequelae in Cervical Spine Facet Injuries: The Role of Canal Diameter. Lintner, Knight, Cullen, Spine, Vol. 18, No 6, 725-729, 1993.
  14. Complimentary Angles: A Simplification of Sagittal Plane Rotational Assessment in Cervical Instability. Knight, Spine, Vol. 18, No 6, 755-758, 1993.
  15. Comparison of Operative versus Non-Operative Treatment of Lumbar Burst Fractures. Knight, Stornelli, Chan, Devanny, Jackman, Clinical Orthopaedics and Related Research, No 293, 112- 121, August 1993.
  16. Physician Profile: Fact or Fiction. Knight, Wu, McGuckin, Journal of Spinal Disorders, Vol. 9, No 6, pp. 509-517, 1996.
  17. Laparoscopic Anterior Discectomy and Interbody Fusion of the Lumbosacral Spine. Koo, Thirlby, Knight, The Official Journal of the Society of Endoscopic & Laparoscopic Surgeons of Asia (ELSA), Vol. 2, No. 1, 5-7, September, 1996.
  18. Modified Microdiscectomy as a Day Surgery Procedure. Hom, Knight, McGuckin, Meserve Virginia Mason Medical Center Bulletin 50:67-75, fall 1996.
  19. Avascular Necrosis of Lumbar Vertebra, Literature Review and Case Report. Chou, L., Knight, RQ., Spine, Vol. 22, No 16, 1997.
  20. Giant Intrathoracic Schwannoma Presenting with Hemothorax. Salcedo-Wasicek, Knight, Pietro, Low, Virginia Mason Medical Center Bulletin, fall 1997.
  21. Major Spinal Surgery in Septuagenarians. Does it improve Patient Function? Knight, RQ Journal of Spinal Disorders, 1999.
  22. Osteofil Allograft Bone Paste, Clinical and Radiographic Follow-Up: Case Study Review. Knight RQ, Cillo YA, White Paper for Regeneration Technologies, Inc. October 1999.
  23. Arthroscopic Treatment of Gunshot Wounds to the Shoulder. Tarkin IS, Hatzidakis A, Hoxie SC, Giangara CE, Knight RQ, The Journal of Arthroscopic & Related Surgery.
  24. The Long Gamma Nail: Outcomes and Complications. Urban JA, Mormino MA, Tarkin I, Swanson S, Kumagi S, Knight RQ, Journal of Orthopaedic Trauma.
  25. Sagittal Balance. Knight RQ, Jackson R, Stanley E, Lowe TG, Winter RW, White Paper for Scoliosis Research Society Website, September, 2002.
  26. Interobserver Reliability in the Interpretation of Diagnostic Lumbar MRI and Nuclear Imaging. DS. Mulconrey, RQ. Knight, JD. Bramble, S Paknikar, PA. Harty, The Spine Journal, March - April; 6 (2) 2006, 177-184.
  27. Direct-Lateral Lumbar Interbody Fusion For Degenerative Conditions: Early Complication Profile. RQ. Knight, P. Schwaegler, D. Hanscom, J. Roh, The Spine Journal. 2009. 22 (1).
  28. Minimally Invasive Lumbar Interbody Fusion: The Direct Lateral Transpsoas Approach. RQ. Knight. SpineUniverse web site, January, 2009. http://www.spineuniverse.com/displayarticle.php/article4222.html.
  29. Gray-scale Assessment Of Apparent Bone Induction Following Direct Lateral Interbody Fusion of Degenerative Lumbar Discs with rhBMP-2 and Interbody Cage. Knight, Vieco, Robinson. Submitted to The Spine Journal December 2008.
  30. Minimally Invasive Spine Surgery. Knight. Current Concepts in Orthopedic Practice. May 2009.
  31. A Prospective, Randomized, Food and Drug Administration Investigational Device Exemptions Study of Lumbar Total Disc Replacement With the Kineflex™ Artificial Disc Versus the CHARITÉ™ Artificial Disc: Evaluation of Clinical Outcomes at 12 Months From a Single Study Site. Knight, MacLennan, Schwaegler, Roh, Robinson. Submittted to Spine. December 2008.

Text Book Chapters:

  1. Knight, RQ., Thomassen, PF.: Open Anterior Lumbar Interbody Fusion (ALIF): Indications, approaches, techniques and nursing care, Chapter 4, Heim, SE., Davis, J., Waller, S. (eds.): Making Sense of Minimally Invasive Spine Surgery, Medical Education Resources, June 1998.
  2. Knight, RQ., Immediate and Delayed Postoperative Complications, Chapter 16, pp. 238-248, Jacobs, G, Welch,WC. (Eds.): Operative Spine Surgery, Appleton & Lange, December 1998.
  3. Knight RQ, Hansen S, Assessment of Outcomes Following Spine Surgery, Chapter 67, Devlin VJ (ed.): Spine Secrets, Hanley and Befus, Inc., in press.
  4. Zeinedine S, Knight RQ, Adjuncts to Spinal Fusion: Growth Factors and Electrical Stimulation, Lewandrowski KU, Wise DL, Yaszemski MJ, White AA III, Trantolo DJ. (Eds.), Advances in Spinal Fusion: Clinical Application of Basic Science, Molecular Biology, Biomechanics, and Engineering, Chapter 52; 781-790, Marcel Dekker, Inc., 2003.

Abstracts:

  1. Taddonio, RF., Knight, RQ.: Analysis of Sagittal Curves and Midline Compensation in Idiopathic Scoliosis Treated with Luque Segmental Instrumentation. 20th Annual Meeting of the SRS, San Diego, USA September 17-20, 1985.
  2. Taddonio, RF., and Knight, RQ.: Analysis of Sagittal Curves and Midline Compensation in Idiopathic Scoliosis Treated with Luque Segmental Instrumentation. European Spinal Deformities Society First Congress, Rome, Italy April 16-19, 1986.
  3. Pedicle Screw Fixation--Effects on Lumbar Lordosis and the Incidence of Aberrant Screw Placement: "Assessment of Early Results". Knight, Chan, Devanny, Jackman, Montgomery, Hieb, SRS/NASS Pedicle Fixation Workshop, Dallas, Texas March 16-17, 1990.
  4. Neurofibromatosis: Post Laminectomy Kyphosis of the Cervical Spine with Anterior Cord Syndrome. A Case Report and Literature Review. Knight, Hieb, The Journal of the American Paraplegia Society, April 1991, Vol. 14(2), pg. 107.
  5. Comparison of Operative versus Non-Operative Treatment of Lumbar Burst Fractures. Stornelli, Knight, Chan, Devanny, Jackman, The Journal of the American Paraplegia Society, April 1991, Vol. 14(2), pg. 68.
  6. Neurologic Sequelae in Cervical Spine Facet Injuries: "The Role of Canal Diameter ". Lintner, Knight, Cullen, The Journal of the American Paraplegia Society, April 1991, Vol. 14(2), pg. 108.
  7. Laminoplasty for Treatment of Multilevel Cervical Stenosis. Hieb, Knight, The Journal of the American Paraplegia Society, April 1991, Vol. 14(2), pg. 10.
  8. Bone SPECT Utility in Patients referred for Suspected Mechanical Spine Pain. Eisenberg, Knight, Gass, Coates, Lee, Journal of Nuclear Medicine, May 1994.
  9. Outcome Assessment in Elective Spine Surgery. Knight, McGuckin, N M A 100th Anniversary Abstracts of Scientific Papers, pp. 34, 1995.
  10. Single Stage Posterior Fusion for Degenerative Scoliosis: Outcome Assessment. Knight, McGuckin, N M A 100th Anniversary Abstracts of Scientific Papers, pp. 35, 1995.
  11. Bone Healing is Impaired in Ethanol-Fed Rats. Chakkalakal, Novak, Fritz, Mollner, McVicker, Pileri, Garvin, Knight, 23rd Annual Meeting of the Research Society of Alcoholism, Alcohol Clin Exp Res 2000; 24(5) Suppl: 132A.
  12. Screening of Osteoconductive Biomaterials Proposed as Vehicles for Growth Factor Application in Bone Repair. Chakkalakal, Strates, Gravin, Novak, Fritz, Mollner, Knight, 110th Annual Meeting of the Nebraska Academy of Sciences, Proceedings of, p. 58; April 2000.
  13. Osteopenia in Rates Due to Ethanol Consumption and Reduced Food Intake. Chakkalakal, Novak, Fritz, Mollner, McVicker, Pileri, Garvin, Knight, Donohue, 47th Annual Meeting of the Orthopaedic Research Society, p. 135; February 2001.
  14. Medullary Osteogenesis Following Marrow Injury. Bechtold, Knight, Novak, Mollner, Fritz, Chakkalakal, 111th Annual Meeting of the Nebraska Academy of Sciences, Proceedings of, p.41; April 2001.
  15. Response of Rat Femur to an Intramedullary Titanium Wire Implant. Tran, Knight, Novak, Mollner, Fritz, Chakkalakal, 111th Annual Meeting of the Nebraska Academy of Sciences, Proceedings of, p.42; April 2001.
  16. Role of Osteoconduction in the Intramuscular Bioassay for Osteoinductive Activity. Meisterling, Knight, Novak, Mollner, Fritz, Chakkalakal, 111th Annual Meeting of the Nebraska Academy of Sciences, Proceedings of, p.42; April 2001.
  17. Treatment of Bone Defects with Combination of BMP-2 and PDGF-AA. Chakkalakal, Strates, Novak, Fritz, Mollner, Knight, 111th Annual Meeting of the Nebraska Academy of Sciences, Proceedings of, p.43; April 2001.
  18. Effects of Alcohol on Cell Function in a Bone Repair Model. Chakkalakal, Mollner, Langan, Fritz, Novak, Knight, Donohue, White, Wilkin, 112th Annual Meeting of the Nebraska Academy of Sciences, Proceedings of, p.48; April 2002.
  19. Acceleration of Bone Formation in Injured Marrow Cavity by TGF-Beta. Kakarlapudi, Gritz, Mollner, Langan, Novak, Cullen, Knight, Chakkalakal, 112th Annual Meeting of the Nebraska Academy of Sciences, Proceedings of, p.47-48; April 2002.
  20. Methods to increase Bone Ingrowth in Noncemented Hip Replacement in the Elderly. Chakkalakal, Redepenning , Garvin, Novak, Fritz, Mollner, Knight, 112th Annual Meeting of the Nebraska Academy of Sciences, Proceedings of, p.47; April 2002.
  21. Validity of the Intramuscular Bioassay for Osteoinductive Activity. Meisterling, Strates, Knight, Novak, Mollner, Gritz, Chakkalakal, 48th Annual Meeting of the Orthopaedic Research Society, February 2002.
  22. Canine Model for Noncemented Hip Reconstruction in the Elderly. Chakkalakal, Redepenning, Garvin, Novak, Fritz, Mollner, Knight, 48th Annual Meeting of the Orthopaedic Research Society, February 2002.
  23. The Relationship between Vascular Endothelial Growth Factor 164 Isoform mRNA Expression and Bone Healing. Patel P, Langan A, Johnson M, Clemens D, Mollner T, Fritz E, Novak J, Knight R, Chakkalakal D. 49th Annual Meeting of ORS, New Orleans, Louisiana, February 2003.
  24. Transforming Growth Factor-Beta 1 Accelerates New Bone Formation after Medullary Reaming. Kakarlapudi R, Fritz E, Mollner T, Novak J, Langan A, Knight R, Chakkalakal D. 49th Annual Meeting of ORS, New Orleans, Louisiana, February 2003.
  25. Methods to improve Noncemented Fixation of Hip Prosthesis in the Elderly. Chakkalakal D, Redepenning J, Garvin K, Novak J, Fritz E, Mollner T, Knight R. 49th Annual Meeting of ORS, New Orleans, Louisiana, February 2003.
  26. Effects of Alcohol on Cell Function in a Bone Repair Model. Chakkalakal D, Mollner T, Langan A, Fritz E, Novak J, Knight R, Hoarah J, White R, Witkin D, Donohue T Jr., 49th Annual Meeting of ORS, New Orleans, Louisiana, February 2003.
  27. The Relationship between Vascular Endothelial Growth Factor 164 Isoform mRNA Expression and Bone Healing. Patel P, Langan A, Johnson M, Clemens D, Mollner T, Fritz E, Novak J, Knight R, Chakkalakal D. National Student Research Forum, Galveston, Texas, April 2003.
  28. Stimulation of Medullary Osteogenesis by TGF-1 and IGF-1. Babbel D, Fritz ED, Mollner TJ, Novak JR, Langan A, Knight RQ, Chakkalakal D. National Student Research Forum, Galveston, Texas, April 2003.
  29. COX-2 Inhibition Delays Formation of Mature Bone by Osteoblasts. Macalena JA, Knight RQ, Mollner TJ, Langan A, Gritz ED, Novak JR, Adickes ED, Chakkalakal D. National Student Research Forum, Galveston, Texas, April 2003.